It seems like only yesterday Meat Boy and Bandage Girl were escaping from an exploding laboratory in the sky. Now it’s the current year, and they’ve welcomed their daughter Nugget into the world. Their days enjoying life as a family came to an abrupt end when Dr. Fetus beat the snot out of them with a rusty shovel, and kidnapped Nugget! Now it’s up to Meat Boy and Bandage Girl to rescue their daughter from a lunatic fetus in a jar that can only be described as an incel version of Nikola Tesla.